CDMOs in Spain: 30 compared (2026)
30 of the 255 contract development and manufacturing organisations in A4BEE’s European census are headquartered in Spain. The largest, with revenue over €1bn, are ESTEVE (Química / CDMO), Insud Pharma (Chemo), mAbxience and Rovi Pharma Industrial Services. 13 sit between €250m and €1bn and 13 are smaller or niche.
By ownership: 14 family-owned, 2 private equity, 4 listed and 10 part of a pharma or industrial group. The most common capabilities are small-molecule API (17), oral solid dose (13), sterile fill-finish (11), microbial and protein (7) and biologics and biosimilars (4). 25 of the 30 rows rest on audited reports or official company disclosures; the rest come from secondary sources or estimates.
30 companies
CDMOs in Spain
| Company | HQ | Ownership | Size | Revenue (as reported) | Modalities | Data |
|---|---|---|---|---|---|---|
| ESTEVE (Química / CDMO)Self-described 'Champion Small-Molecule CDMO'; APIs, HPAPIs and advanced intermediates for third parties. | Barcelona | Family-ownedEsteve family | Tier 1 | not disclosed | Small-molecule API | high |
| Insud Pharma (Chemo)Group-level entity. Chemo industrial division provides CMO/CDMO across most dosage forms incl. injectables. Parent of Liconsa and León Farma. | Madrid | Family-ownedGrupo Insud | Tier 1 | not disclosed | Small-molecule API, Oral solid dose, Sterile fill-finish, Biologics and biosimilars, Monoclonal antibody | high |
| mAbxienceBiosimilar developer and biologics CDMO; fully single-use technology at León. CDMO services confirmed. | León | Part of a pharma or industrial groupFresenius Kabi | Tier 1 | not disclosed | Monoclonal antibody, Biologics and biosimilars, Microbial and protein | high |
| Rovi Pharma Industrial ServicesBest-known Spanish injectables fill-finish CDMO; performed fill-finish of the Moderna COVID vaccine. Rebranded 'Rois' (2024). | Madrid | ListedLaboratorios ROVI | Tier 1 | Group ROVI ~€1.0 bn | Sterile fill-finish, Oral solid dose, Small-molecule API | high |
| BioibéricaWorld-leading producer of heparin API + other biological-origin APIs; offers contract/custom manufacturing. CDMO role secondary. | Palafolls | Part of a pharma or industrial groupSARIA Group | Tier 2 | not disclosed | Biologics and biosimilars | medium |
| Farmhispania GroupIndependent private API CDMO; leading European CDMO in HPAPI (cytotoxics) plus fermentation and large-scale lyophilisation. | Montmeló | Family-owned | Tier 2 | not disclosed | Small-molecule API, Microbial and protein | high |
| Interquim (Ferrer)API arm of Spanish pharma group Ferrer; develops/manufactures APIs with custom synthesis and contract manufacturing. | Sant Cugat del Vallès | Part of a pharma or industrial groupFerrer | Tier 2 | not disclosed | Small-molecule API | high |
| Kern PharmaDedicated 'Production to Third Parties' line. 3rd-largest Spanish generics producer by volume; chemical plant synthesises APIs. | Terrassa | Family-ownedGrupo Indukern | Tier 2 | not disclosed | Oral solid dose, Small-molecule API | high |
| Laboratorios León FarmaThird-party make-to-order manufacturer; dedicated hormonal OSD/contraceptives (tablets, caps, vaginal rings, semisolids). | Villaquilambre | Part of a pharma or industrial groupInsud Pharma | Tier 2 | not disclosed | Oral solid dose | high |
| Laboratorios LiconsaThird-party contract manufacturing. FDF specialist: tablets, capsules, pellets, soft-gel, creams, inhalers. | Azuqueca de Henares | Part of a pharma or industrial groupInsud Pharma | Tier 2 | not disclosed | Oral solid dose | high |
| Laboratorios NormonPrimarily own-product generics leader; offers CMO services via its International Division. CMO is a secondary line. | Tres Cantos | Family-owned | Tier 2 | not disclosed | Oral solid dose, Sterile fill-finish, Small-molecule API | medium |
| Laboratorios SalvatCDMO division specializes in sterile BFS liquids and single-dose ophthalmic/otic/nasal formulations. | Barcelona | Family-ownedPeris family | Tier 2 | not disclosed | Sterile fill-finish, Oral solid dose | high |
| Moehs GroupIndustrial holding producing APIs + CDMO/custom-manufacturing; >75 products, >80 DMFs. Founded 1962. | Rubí | Part of a pharma or industrial groupPMC Global (US) | Tier 2 | ~€40 m/yr (Moehs Ibérica) | Small-molecule API | high |
| Reig JofreMarket leader in complex generics; CDMO covers sterile/lyophilized injectables plus beta-lactam antibiotics in segregated facilities. | Sant Joan Despí | Listed | Tier 2 | €339 m (2024) | Sterile fill-finish, Small-molecule API, Oral solid dose | high |
| SUANFARMASpain-HQ B2B life-sciences; CDMO offers end-to-end small-molecule dev/manufacturing combining fermentation and synthesis. | Alcobendas | Private equityArchiMed | Tier 2 | not disclosed | Small-molecule API, Microbial and protein | high |
| UQUIFAAPI manufacturer with explicit CDMO franchise (off-patent APIs + custom development). ~85 yrs history. | Barcelona | Part of a pharma or industrial groupVivimed Labs (India) | Tier 2 | not disclosed | Small-molecule API | high |
| Viralgen Vector CoreOne of Europe's largest dedicated AAV gene-therapy vector CDMOs; founded 2017 as an AskBio subsidiary, now within Bayer. | San Sebastián | Part of a pharma or industrial groupBayer (AskBio) | Tier 2 | not disclosed | Viral vector and vaccine, Cell and gene therapy | high |
| 3PBIOVIANMerger of 3P Biopharmaceuticals (Spain) + Biovian (Finland). | Noáin | Private equityKeensight | Tier 3 | ~US$81 m | Microbial and protein, Viral vector and vaccine, Cell and gene therapy | medium |
| 53BiologicsSpanish biologics CDMO (2017); recombinant proteins from DNA to protein — cell line dev, banking, GMP manufacturing. | Boecillo | Family-owned | Tier 3 | not disclosed | Biologics and biosimilars, Microbial and protein | medium |
| Combino PharmGenerics developer that licenses out dossiers and offers third-party contract manufacturing, mainly via its Malta plant. | Sant Joan Despí | Family-ownedCorporación Medichem | Tier 3 | not disclosed | Sterile fill-finish, Oral solid dose, Small-molecule API | medium |
| CovexIndependent Spanish API maker since 1977; specialist in vinca alkaloids. CMO/CDMO for third-party API manufacturing. | Colmenar Viejo | Family-owned | Tier 3 | not disclosed | Small-molecule API | high |
| DeretilGlobal leader in side chains for beta-lactam antibiotics; custom synthesis/enzymatic chiral tech. Founded 1961. | Cuevas del Almanzora | Family-owned | Tier 3 | not disclosed | Small-molecule API, Microbial and protein | high |
| Ercros (Pharmaceuticals)Listed chemicals group; pharma division makes generic APIs (antibiotics via fermentation) AND custom/contract manufacturing. | Aranjuez | Listed | Tier 3 | not disclosed | Small-molecule API, Microbial and protein | high |
| GP PharmCDMO focused on highly complex injectables: peptides, oligonucleotides, hormones, liposomes and microspheres. FDA-inspected. | Sant Quintí de Mediona | Family-ownedParente family | Tier 3 | not disclosed | Peptide, Sterile fill-finish | high |
| IdifarmaNiche small-molecule CDMO specialising in HPAPI/oncology small-batch manufacturing and spray-drying. | Pamplona | Part of a pharma or industrial groupArdena | Tier 3 | not disclosed | Small-molecule API, Oral solid dose | high |
| LabianaCDMO/CMO for human and animal health; sterile liquids, non-sterile solids, sterile injectable + freeze-dried forms. BME Growth-listed. | Corbera de Llobregat | Listed | Tier 3 | €66 m (2024) | Sterile fill-finish, Oral solid dose | high |
| Laboratorios Alcalá Farma'Leading CDMO in Spain' (20+ yrs); broad dosage forms incl. soft-gel caps, stick-packs, sterile/injectable, lyophilised. Owned by Synerlab. | Alcalá de Henares | Part of a pharma or industrial groupSynerlab | Tier 3 | not disclosed | Oral solid dose, Sterile fill-finish | high |
| PrasfarmaCMO/CDMO specialized in cytostatics, HPAPI and oncology; aseptic fill/lyophilization plus solid forms. Annex-1. | Cerdanyola del Vallès | Family-owned | Tier 3 | not disclosed | Sterile fill-finish, Oral solid dose | high |
| Praxis PharmaceuticalCDMO for dev + contract manufacturing of liquid and lyophilised sterile injectables incl. biologics and orphan drugs. Annex-1. | Vitoria-Gasteiz | Family-owned | Tier 3 | not disclosed | Sterile fill-finish | high |
| Quality ChemicalsIndependent Spanish CDMO (40+ yrs) specializing in inorganic/organic salts in API and excipient grades. GMP/ISO. | Esparreguera | Family-owned | Tier 3 | not disclosed | Small-molecule API | high |
Size: Tier 1 (revenue over €1bn) · Tier 2 (€250m–€1bn) · Tier 3 (under €250m or niche).
Revenue, staff and site figures are as reported and mix audited accounts with commercial estimates, which are often wrong for private companies. Each row carries a confidence mark; verify a figure before quoting it.
Browse the census
Other European CDMO lists
By country
- CDMOs in Italy (31)
- CDMOs in Spain
- CDMOs in Germany (28)
- CDMOs in the United Kingdom (25)
- CDMOs in France (15)
- CDMOs in Switzerland (14)
- CDMOs in Poland (11)
- CDMOs in Belgium (9)
- CDMOs in Sweden (9)
- CDMOs in Greece (8)
- CDMOs in Ireland (8)
- CDMOs in the Netherlands (8)
- CDMOs in Portugal (8)
- CDMOs in Denmark (7)
- CDMOs in Austria (5)
- CDMOs in Finland (5)
- CDMOs in Norway (5)
- CDMOs in Czechia (4)
- CDMOs in Lithuania (4)
- CDMOs in Bulgaria (3)
By modality
- Small-molecule API CDMOs in Europe (107)
- Oral solid dose CDMOs in Europe (94)
- Sterile fill-finish CDMOs in Europe (106)
- Biologics and biosimilars CDMOs in Europe (66)
- Monoclonal antibody CDMOs in Europe (36)
- Antibody-drug conjugate (ADC) CDMOs in Europe (15)
- Cell and gene therapy CDMOs in Europe (29)
- mRNA and LNP CDMOs in Europe (22)
- Viral vector and vaccine CDMOs in Europe (32)
- Microbial and protein CDMOs in Europe (34)
- Peptide CDMOs in Europe (24)