Which automated sampler fits your process?

Entry-level bioPROBE: one filterless probe per vessel feeding a 36-position orbitSAM carousel (storage only, no analyzer coupling). The 'from 2 min' interval comes from an archived BBI spec table; the live site no longer publishes one.

Four independent bioPROBEs feeding one multiSAM with up to 384 cooled positions, named analyzer packs (MACSQuant, Vi-CELL XR) and a 21 CFR Part 11 audit-trail pack. No four-reactor throughput figure is published.

Discontinued — BBI's product page now redirects permanently and iceBLOCK (96 Peltier positions) takes its slot. Listed because installed units exist, and it can heat as well as cool samples in the vial (0 to +100 °C).

A passive single-use 'seal-and-store' manifold for Xcellerex XDR bioreactors and XDUO/XDM mixers — an operator draws into a bag and seals it. Cytiva publishes no datasheet, and we found no bag volume stated anywhere.

Listed for completeness: a bioprocess control station with PAT signal I/O but no documented automated sampling. Distek's autosampler belongs to its dissolution line, an unrelated product family.

Bolts directly onto Eppendorf's own DASware-controlled bioreactor line (DASbox, DASGIP, SciVario twin, BioFlo 320) — deep, retrofit-friendly integration but zero cross-brand support. It is a sample COLLECTOR, not an analyzer feeder: draws into a chilled vial for offline analysis, with a reusable needle and wash cycles rather than a single-use fluid path.

The workhorse Seg-Flow: reusable pinch-valve hardware that routes native or pre-diluted samples from up to 8 vessels to downstream analyzers, vendor-agnostic on both ends. Flownamics publishes no dilution ratio; storage is the separate FlowFrac 1000.

The S3 chassis re-plumbed for blood-gas analyzers (pH, pCO₂, pO₂) so dissolved gases don't escape before the read. Flownamics publishes no interval or volume for the S3G itself — the 10–45 min and 1.25–50 mL often quoted belong to the S3.

Seg-Flow for cell & gene therapy: a fully disposable, low-shear fluid path per bioreactor, trading reusability for zero cross-contamination risk. Up to 16 modules in parallel per Flownamics' own spec table; no sampling interval is published.

Lonza's platform until Merck bought it in 2022; positioned for GMP stainless-steel manufacturing, not just bench R&D. No minimum sampling interval is published, and storage and dilution come from an optional Gilson liquid handler.

Manual, not automated: a single-use, no-dead-leg sampling unit for stainless-steel and multi-use processes — Merck's option for sites that haven't automated sampling. The standard GO unit is not autoclavable; a separate autoclavable line exists.

Single-use sibling of NovaSeptum GO: same closed, no-dead-leg draw, but welded or connected into a single-use train. Manual. Volumes are Merck's summary-table figures — individual SKUs differ, so check the part number.

Connects Nova's FLEX2 bench analyzer to up to 10 bioreactors with automated draws, roughly hourly per vessel. Every reading consumes Nova's proprietary MicroSensor Card. Each draw pulls 5.6 mL from the reactor; chilled storage is an optional extra.

Nova's module, though often credited to Sartorius. Not a bioreactor-side sampler: the Ambr robot draws the sample and dispenses it into a cup on the ESM deck, so sterility comes from the Ambr cabinet.

Not an autosampler: a pH and Raman measurement accessory the Ambr robot pipettes into, so it competes with the analyzer half of the chain. The read is destructive — no storage, no dilution. Specs follow Sartorius' current brochure; older editions quote other volumes and cycle times.

Modular multiplexer, dilution, filtration and routing stack built to feed many downstream instruments (HPLC, Cedex Bio HT, Vi-CELL, Nova FLEX2) rather than one brand. Specs are Numera 3; an installed V2.x runs to older limits, so confirm the generation.

Chip-based nanoelectrospray source and infusion robot, made by Advion Interchim Scientific (sometimes miscredited to Gilson). Works with several third-party MS platforms, including Waters and Sciex.

Agilent's standard-throughput UHPLC autosampler — single-needle design pitched at routine QA/QC and method-development labs that don't need the Multisampler's dual-needle speed or 6,000+ sample capacity.

Dual-needle design overlaps sample draw with the previous injection cycle, pushing cycle time down to ~5 s and capacity up to 6,144 samples — built for high-throughput labs running unattended batches, not routine single-sample QC.

Purpose-built loading accessory for Bio-Rad's BioLogic DuoFlow protein purification system rather than a standalone chromatography autosampler; optional Peltier cooling protects heat-sensitive protein/antibody samples during queued injections.

Legacy refrigerated autosampler for Bio-Rad's discontinued BioLogic HR/HRLC systems; no longer listed in Bio-Rad's current catalog and only available through the used-equipment secondary market, illustrating that Bio-Rad has since exited direct autosampler manufacturing in favor of NGC-to-third-party integration.

Split-loop LC-MS autosampler for Bruker's Elute+ platform, tuned for the low-carryover, high-reproducibility injections that QC/release LC-MS/MS methods (e.g., pesticide, residue panels) require; ships with PFAS-free flow-path options.

High-throughput sample-handling tier of the Elute+ platform built around a third-party CTC Analytics PAL RSI autosampler rather than a Bruker-native mechanism, expandable with additional sample trays for high-volume QC/release workflows and online extraction.

Compact NMR sample changer for Bruker Avance spectrometers, using interchangeable cassette modules with a built-in barcode reader — aimed at standard-throughput NMR QC service labs rather than the very-high-throughput SampleJet line.

Entry-level companion to SampleXpress with a smaller removable carousel, aimed at labs that need basic batch NMR sample submission without full SampleXpress cassette capacity.

Bruker's original automated NMR sample-changer line (predates SampleXpress), offered in 60- and 120-position configurations for unattended queued acquisitions across a wide range of Bruker field strengths.

Entry-level automated injector with manually exchanged tools; supports liquid, headspace and SPME sampling on one modular platform and is field-upgradeable to full PAL RTC tool-changing. OEM'd across Agilent, Thermo, Shimadzu and other GC/LC brands.

Robotic tool-changer that switches between liquid injection, headspace and SPME within one sample list in under 30 seconds, enabling unattended 24/7 multi-technique workflows. OEM'd widely across instrument brands rather than sold only under the CTC/Trajan name.

Two independent robotic heads run parallel workflows (e.g. simultaneous headspace prep plus GC/LC injection into two systems), roughly doubling throughput versus single-head RTC/RSI configurations for high-volume QC/release labs.

Gilson's high-throughput SPE/cartridge automation platform (1/3/6 mL cartridges), built as an open modular liquid handler intended to bolt onto third-party LC/MS front ends rather than a closed proprietary analytical stack.

Dedicated static-headspace autosampler that heats/shakes up to 6 vials simultaneously and relocates between GC systems from different brands in under 5 minutes; the 2000HT variant extends oven/syringe temperature for high-boiling-point applications.

Single autosampler head that covers liquid, static headspace and SPME injection and switches between the three modalities in about 5 minutes without hardware changes — a lower-cost, single-technique-at-a-time alternative to CTC's true tool-changing PAL RTC.

Routine, general-purpose autosampler in JASCO's LC-4000 series for conventional HPLC; full-loop mode maximizes reproducibility for repeat serial injections, partial-loop mode lets users change injection volume without swapping loops.

RHPLC-tier autosampler rated to 70 MPa with sub-30-second injection cycles; an optional 5-solvent flush system pushes carryover toward zero for trace-level QC/release methods.

UHPLC-tier sibling of the AS-4150, rated to 130 MPa with tighter injection precision — JASCO's top-of-line LC-4000 autosampler for high-resolution UHPLC QC methods.

Large-volume/preparative member of the LC-4000 autosampler family, standard up to 5 mL injections (10 mL optional) for prep-scale and semi-prep QC workflows where analytical-tier loop sizes fall short.

Space-saving 15 cm-wide autosampler that can be bolted onto an existing (including non-JASCO) LC stack via keypad or RS-232 control, rather than requiring the full LC-4000 system controller.

KNAUER's flagship AZURA-series autosampler, offered in analytical, preparative, and biocompatible configurations sharing one chassis; the analytical build adds an ILD valve that depressurizes the loop pre-aspiration to prevent solvent dilution of the sample.

Faster UHPLC-tier autosampler for KNAUER's PLATINblue system — sub-15-second injections (under 60 seconds with a full needle wash) aimed at high-throughput UHPLC QC/release testing, versus the AZURA line's HPLC/prep focus.

Modular autosampler for the Flexar HPLC platform; offers three injection modes (full loop, partial fill, µL sampling) with no sample waste and an optional Peltier-cooled sample compartment for temperature-sensitive QC samples.

UHPLC-tier autosampler built for the LC 300 system, using PerkinElmer's patented 7-port Intermediate Loop Decompression (ILD) valve to depressurize the loop before sampling — improving injection accuracy/reproducibility and extending column life.

Long-running, widely-deployed autosampler explicitly marketed to work with virtually any LC system, not just PerkinElmer's; upgradable to a biocompatible flow path and supports on-board dilution/derivatization/standard-addition without extra hardware.

Pre-certified 2.0 mL screw-thread vial/cap/septa kits, batch-tested for dimensional fit, septum reseal, and LC/GC extractable residue so labs can skip incoming QC. Fits the standard 2 mL vial format used across virtually all GC/LC autosampler brands.

20 mm crimp-top headspace vials in multiple volumes purpose-built for static/dynamic headspace autosamplers (HTA, CTC/PAL, Agilent, PerkinElmer); flat- or round-bottom options trade fill precision for sampler-arm clearance.

OEM-equivalent replacement syringes (Hamilton-manufactured, Restek-supplied) sized and needle-configured to match specific autosampler brands (Agilent, CTC/PAL, Thermo, HP) — buyers must match the exact syringe model to their sampler rather than use a universal part.

Shimadzu's flagship UHPLC autosampler family, sold only as part of the Nexera LC stack; the CX3 variant targets ultra-low-carryover bioanalytical/pharma QC injections.

Compact, lower-cost online-SPE autosampler positioned below Symbiosis Pharma; aimed at labs that need automated sample cleanup ahead of LC-MS/MS without flagship-level throughput.

Flagship high-throughput online SPE-LC-MS platform for direct injection of raw biological samples (e.g. plasma); switches between LC-MS, XLC-MS (online SPE), and AMD method-development modes for pharma bioanalysis labs.

Split-loop UHPLC autosampler with machine-learning-based wash-solvent monitoring and vial-bottom detection to inject from as little as 2 µL — Thermo's flagship analytical (LC) sampler for Vanquish Horizon/Flex systems, a genuinely distinct family from the GC-focused TriPlus and IC-focused Dionex.

GC/GC-MS robotic sample handler, not an LC autosampler — Automatic Tool Change lets one unit run liquid, headspace, and SPME Arrow injections plus sample-prep cycles (dilution, derivatization) in a single unattended sequence; ships with mounting kits for Thermo's own TRACE GCs and for major third-party GCs.

Ion-chromatography-dedicated autosampler with an all-PEEK flow path to avoid metal contamination of IC eluents — a genuinely distinct product family from the LC-focused Vanquish and GC-focused TriPlus, built specifically around Dionex ICS integration.

Flow-through-needle design makes the needle itself part of the high-pressure flow path, cutting dead volume and carryover — Waters' core UPLC autosampler, extendable with loop kits for larger injection volumes.

Danaher's flagship dual-arm liquid-handling workstation for genomics/proteomics/synthetic-biology workflows — a distinct product line from Cytiva's Xcellerex bioprocess sampling hardware despite the shared Danaher parent.

Hamilton's best-known liquid-handling platform, built around proprietary CO-RE tip technology and heavily used as a genomics/diagnostics automation backbone with third-party instrument integration via Hamilton's VENUS driver library.

Hamilton's newer modular flagship alongside STAR, aimed at higher-throughput, tighter-integration labs; Hamilton publishes less granular public numeric detail on Vantage than on STAR.

Tecan's long-running modular workhorse platform, widely deployed as a cross-vendor automation hub via EVOware device drivers rather than a closed single-brand system.

Tecan's current-generation flagship, positioned as the successor workhorse to Freedom EVO with a smaller footprint and FluentControl software for cross-instrument work-cell integration.

Auto-dilution flame/hydride AAS autosampler for Analytik Jena's novAA/ZEEnit spectrometer lines, performing single-step dilutions up to 1:800 to extend calibration range without manual sample prep — sold as an instrument-specific accessory rather than a cross-vendor sampler. Analytik Jena has been part of the Endress+Hauser Group since 2019.

Teledyne CETAC-built ASX-560 autosampler integrated and sold by Analytik Jena for its ICP-OES/ICP-MS instruments, with an integrated rinse station; the SimPrep variant adds inline dilution up to 1:2500 for automated calibration-standard preparation.

Flagship syringe-pump dissolution autosampler; valve-free, low-volume (4.5 mL) flow path minimizes carryover, with an optional lower-cost 'child' unit to sample a second bath independently.

Prior-generation syringe-pump dissolution sampler; single or dual 8-channel syringe pump configuration lets one unit run two independent dissolution methods with full audit logging.

Stationary refrigerated water/process sampler for continuous compliance and process monitoring (wastewater, surface water, industrial process streams), with up to 4 Memosens digital sensor channels for inline parameter logging alongside discrete bottle sampling. List pricing is quote-only per configuration.

Portable, battery-powered counterpart to the CSF48 for spot/campaign water sampling in the field (e.g. stormwater or industrial discharge audits), supporting up to 2 Memosens digital sensors and an 8 m suction lift on a 19 kg chassis.

High-capacity robotic-arm sample processor for Metrohm titration/IC workflows, handling up to 999 sample positions across racks up to 42 cm diameter with inline dilution, filtration and preconcentration under MagIC Net — locked to the Metrohm instrument/software ecosystem, not vendor-agnostic.

USB-networked robotic sample processor for parallel titration/dosing workstations, sold in 1T/2T configurations with 0–2 integrated membrane pumps; built around Metrohm's proprietary MSB device-daisy-chain interface rather than a generic automation bus.

Small-volume x-y-z autosampler for IC/HPLC optimized for speed (sub-10-second sample delivery) and micro-volumes down to 1 µL, with double-needle septum piercing and Pressure-Assisted Sample Aspiration across full-loop, partial-loop and pick-up injection modes.

Entry-tier InMotion model for lower-volume KF and titration labs; scales from large beakers to small glass tubes but only within Mettler-Toledo's own One Click instrument ecosystem.

Mid-tier InMotion model with roughly 3-4x the sample load of Flex; adds an optional barcode reader for sample tracking in regulated QC titration workflows.

Top-of-range InMotion tier built for high-throughput central labs running large unattended overnight KF/titration batches.

Modular sample manager sold as a SOTAX Xtend system component; functions as either a simple fraction collector or a full HPLC/UPLC direct-injection autosampler for dissolution testing.

Floor-standing fully automated dissolution system that self-preps media, fills vessels, samples/filters, and self-cleans unattended end-to-end — the top tier above the semi-automated ATS Xtend.

The high-capacity autosampler in CETAC's family — built to feed ICP-MS/ICP-OES/AA instruments across OEM brands (Thermo, Cytiva AKTA) rather than being locked to one analyzer vendor.

Compact sibling to the ASX-560, sized for benches with less real estate; explicitly qualified across Thermo's iCE/iCAP/Element instrument families, not a single-vendor add-on.

Liquid-handling add-on that rides on the ASX-560/280 chassis to automate dilutions, spikes and calibration curves upstream of AA/ICP-OES/ICP-MS — sample prep, not just sample delivery.

Portable field autosampler for stormwater/wastewater compliance monitoring; standalone unit (not tied to a specific analyzer ecosystem), built for manhole and field deployment rather than fixed-lab automation.

Modular portable autosampler line with 1/4/8/24-bottle distributor-arm configurations, letting one base unit scale from spot checks to full 24-bottle discrete compliance sampling.

Chemspeed's flagship modular synthesis deck — SBS-plate-based, tool-exchange architecture spans conventional, microwave, photochem and reactive-gas chemistry; vendor-agnostic by design, the closest thing to a self-driving-lab backbone in the portfolio.

Mid-tier scalable platform positioned between the entry CRYSTAL and the flagship FLEX — application-tuned for analytics/preformulation sample prep with a moving-balance gravimetric design rather than fixed liquid-handling heads.

Chemspeed's compact entry point into automation — pure gravimetric solid dispensing on a benchtop footprint, positioned as the on-ramp before a lab scales into SWING or FLEX.

Concentration + size from the same 2 µL draw — UV/Vis, DLS and SLS in one read, cutting the multi-instrument relay biologics formulation teams usually run for quantification and aggregation checks.

Dedicated high-throughput thermal/colloidal stability screener (Tm, Tagg) — narrower-purpose than the multi-modal Uncle/Aunty lines, positioned for teams that just need fast go/no-go stability ranking across formulations.

LNP/nanoparticle formulation production line, not an analyzer — Sunscreen screens formulations, Sunshine scales process development toward continuous multi-liter output, both riding on reusable glass 'Sunnies' microfluidic chips.

Unchained's 2026 entrant into generative-AI-driven lab automation — natural-language-to-workflow execution (built on Anthropic's Claude) on a fully modular deck, aimed squarely at Chemspeed's FLEX/SWING territory but differentiated by native LLM experiment design.

908 Devices sold its desktop bioprocessing/PAT line (MAVEN, MAVERICK, REBEL, ZipChip) to Repligen for $70M cash in March 2025 and refocused on handheld chemical-ID devices — it no longer competes in the benchtop bioprocess/sampling market this catalog tracks.